HAMAK HOTELS x ORA
boutique intelligent regenerative
EXPERIENCES SPACES FUTURES

HAMAK HOTELS x ORA
Embedding Regenerative Intelligence into Hotel Properties & Experiences
OVERVIEW
ORA is a regenerative design and operations suite that installs biological intelligence into hospitality spaces-not merely as a retreat, not a clinical programs menu, but as an embedded system. In partnership with HAMAK HOTELS, we propose a complete Wellness and Longevity layer strategy across flagship properties that will:
Unlock new revenue streams (clinical, therapeutic, virtual, retail)
Differentiate Hamak Hotels as the first regenerative hotel portfolio in LATAM
Extend guest stays, increase return cycles, and deepen brand loyalty
ABOUT ORA
ORA is an emerging regenerative design and operations suite pioneering a new category in hospitality where biology, architecture, and longevity converge. While ORA is new in name, it is decades in the making. Founded by Dr. Denisa Rensen and Beatrice Etzold, our team brings a rare fusion of clinical expertise, longevity science, and sensory design rooted in years of experience across the fields of regenerative medicine, elite wellness, and boutique hospitality.
We are not building a retreat or layering on spa services. We are installing a living system, one that restores coherence to human biology in environments that feel exquisite. Our approach is both precise and poetic, drawing on ancient healing systems and future-forward medical technologies to create deeply therapeutic spaces that regenerate the nervous system, fascia, mitochondria, and spirit.
ORA works with an international board of physicians, scientists, and longevity experts from the US, Canada, EU, and Mexico. Our clinical layer is directed by licensed MDs and regenerative specialists who operate with Swiss-level safety protocols and COFEPRIS compliance. Every protocol, every tool, and every guest pathway is designed with one question in mind: what is the most intelligent, beautiful, and biologically sound way for a human to heal?
THE ORA MODEL
Current Hamak Hotels offerings focus on high-touch design and experiential hospitality. But guests seeking healing, optimization, regenerative & longevity therapies and long-lasting transformation are spending significant sums at other boutique wellness resorts and with private concierge clinics.
By integrating ORA, Hamak Hotels captures this market without disrupting the brand tone or operational model.
Our three-tier system meets guests where they are:
WELLNESS LAYER (non-clinical)
Subtle, somatic, and elegant, this layer embeds non-invasive, high-impact therapeutic experiences into the guest's natural rhythm. It is designed to regulate the nervous system, restore fascia and lymphatic flow, enhance mitochondrial function, and elevate the emotional and sensory experience through architectural and biophilic interventions. Therapies are delivered through ambient biophysics-based tools (PLASM biophysics, PEMF, red light, Muse-guided neuroacoustics), hands-on rituals (Shiatsu, craniosacral, fascia release), and internal supports (botanical elixirs, hydration protocols, regenerative menus). The Wellness Layer is architecture-as-therapy-deep healing, without disruption, licensed or clinical requirements.
REGENERATIVE LAYER (clinical)
Precision, potency, and cellular repair. This layer delivers COFEPRIS-compliant advanced longevity medicine-including IV nutrient protocols, biologics, peptides, hormones and regenerative injections. Designed for deeper biological intervention, it uses diagnostics (genomics, telomere length, HRV, inflammatory and hormonal panels) to personalize each guest’s protocol. Treatments are administered on-site or via mobile medical units, under physician oversight. The Regenerative Layer activates stemness, reverses biological aging, and initiates systemic repair-all within the aesthetic, sensorial framework of ORA’s hospitality design.
BLUEPRINT LAYER (virtual)
The post-stay arc of transformation. This layer ensures continuity of care and loyalty through personalized long-tail protocols. Guests receive a digital regenerative blueprint with virtual follow-up sessions, curated supplement and peptide deliveries, seasonal recalibration guidance, and integration check-ins. It encourages return visits every 3–6 months across Hamak Hotels properties, converting one-time guests into ongoing members of a regenerative journey.
THE ORA DISTINCTION: INTEGRATION
ORA offers a unique opportunity to build regenerative hospitality from within Hamak Hotels. While many leading wellness partnerships focus on clinical programming or external brand licensing, ORA seamlessly integrates the WELLNESS, REGENERATIVE and BLUEPRINT layers with Hamak Hotels’ existing properties, tone, and operational model. We design each therapeutic arc in harmony with the architecture, biophilic aesthetic, and brand essence of the hotel itself—transforming healing into a natural, elegant part of the guest experience.
Our model begins with rhythm, space, and sensation, allowing biology to be introduced where it fits most effortlessly. We adapt each wellness and longevity offering to the specific cultural, spatial, and emotional feel of the location. Our design-led regenerative layer is fully COFEPRIS-compliant, while preserving the intimate and immersive tone Hamak Hotels guests expect. Treatments are subtle, embedded, and beautifully delivered. Guests do not feel like they are visiting a clinic, they feel as though their biology is being honored from within the property they chose to visit.
With ORA, Hamak Hotels also retains full creative control and brand ownership. We can license a pre-built identity or install a one-size-fits-all clinic, or we build a bespoke system that lives within the Hamak Hotels brand. We are flexible in the design and operational needs of each flagship property. Our focus is to create continuity, cohesion, and long-term value for both the brand and its guests.
ORA’s emergence as a new leader in regenerative hospitality also opens powerful storytelling and press opportunities. The market is saturated with established names, yet guests, media, and investors are seeking fresh, intelligent approaches that combine future-forward science with refined, emotionally intelligent experiences and spaces. Hamak Hotels has an opportunity to be not only the first in Latin America to do this, but to do it with originality, elegance, and resonance.

ORA MODALITIES, BY LAYER
ORA offers a complete ecosystem of therapeutic intelligence across three integrated layers: Wellness, Regenerative, and Blueprint. Each layer is a standalone experience, but together they create a continuum of care that moves guests from immersion to transformation to lifelong regeneration.
WELLNESS LAYER
Rooted in ancient rhythms and elevated by contemporary biophysics, the Wellness Layer is ORA’s non-clinical foundation. Designed to soothe, recalibrate, and optimize without intrusion, this layer draws from somatic therapies, neuroaesthetic interventions, fascia work, and ambient energetic technologies. It is for the guest who seeks restoration of coherence of body, breath, sleep, and self. Here, architecture becomes therapy, food becomes signal, and each moment is a sensorial portal into deeper physiological harmony. It is soft power: subtle, sustained, and biologically profound.
Non-clinical, deeply somatic, sensorially immersive.
Core Modalities:
PLASM frequency field therapy (biophysical regulation)
PEMF cellular recharging
Red/NIR photobiomodulation
Muse-guided neuroacoustic entrainment
Botanical elixirs and structured hydration
Thai massage, Shiatsu, Watsu, KiYO, Lipodissolve, craniosacral therapy, fascia release
Hydrotherapy, scrubs, and wraps inspired by traditional European and Japanese spa medicine
Circadian-tuned lighting and sleep optimization technologies
Seasonal menus free from seed oils and processed sugars, personalized by dosha/constitution/microbiome profile
Key Outcomes:
Nervous system coherence
Fascia and lymphatic flow
Mitochondrial support
Sleep restoration
Subtle detoxification and emotional recalibration
REGENERATIVE LAYER
Where the Wellness Layer restores, the Regenerative Layer repairs—deeply, diagnostically, and with medical precision. This is clinical-grade care embedded in sensorial intelligence. Guided by a global team of physicians and scientists, the guest moves through a personalized protocol of advanced diagnostics, injectable biologics, and longevity therapeutics. Every molecule, infusion, and intervention is sourced, formulated, and delivered to Swiss-level safety standards, in spaces that feel more like sanctuaries than clinics. This is not a treatment—it is the future of medicine designed for the human experience.
Medical-grade therapies delivered under clinical oversight, grounded in science, safety, and beauty.
Diagnostics + Personalization: ORA begins with deep biological listening. Each guest receives personalized diagnostics including full biomarker panels (inflammatory markers, HRV, micronutrient levels, hormone panels), telomere and biological age testing, genomic and epigenetic analysis, and microbiome assessment. Guests who arrive with prior advanced testing are encouraged to bring their data, which ORA’s clinical team will review as part of an integrative second-opinion process. This model supports intelligence-first medicine: precision begins with insight.
Clinical Oversight + Swiss-Level Safety: All regenerative therapies are administered in COFEPRIS-compliant environments or sensorially designed suites. ORA is guided by a board of international experts, including leading physicians and scientists from Mexico, the U.S., Canada and Europe. These experts are available onsite or virtually depending on case needs, ensuring that even advanced protocols are delivered safely and with full regulatory alignment. Our protocols follow Swiss-level sterilization and safety standards, positioning ORA as a new benchmark for clinical rigor within hospitality.
Formulation Integrity: Guests access the highest quality biologics, peptides, hormones, and nutraceuticals, produced in our MD-partnered laboratory. With direct oversight on every step of formulation and fulfillment, we ensure clinical-grade purity, proper chain-of-custody, and pharmaceutical-level potency. Guests benefit from customized stacks designed to match their biomarkers, administered during stay and continued via Blueprint Layer follow-up.
Regenerative Interventions:
IV & Injection therapy: NAD+, ozone, high-dose antioxidants, mitochondrial stacks, detox protocols, peptides
Biologics: stem cells, exosomes, PRP, NK cells, CarT cells (where appropriate)
Cellular & medical aesthetics
Hormone recalibration: bioidentical hormone therapy as clinically indicated
Peptide stacks for optimization & longevity
Ongoing Insight + Case Study Publication: With guest consent, ORA collects longitudinal data across biomarkers, subjective well-being, and functional outcomes. This allows us to publish anonymous case studies and contribute to the broader field of longevity and regenerative medicine. Guests become part of an evolving ecosystem of science, story, and human renewal.
The Regenerative Layer is not a spa upgrade-it is the arrival of medicine within beauty, precision within comfort, and healing within coherence.
BLUEPRINT LAYER
True regeneration begins when the stay ends. The Blueprint Layer translates each guest’s in-residence care into a long-term protocol, delivered virtually, seasonally updated, and tied to return visits across Hamak Hotels properties. It is a post-program companion, a digital map of resilience, and a living system of support. With ongoing access to clinicians, curated formulations, and a sense of being held in a regenerative arc, guests move from transient healing to lifelong vitality. The Blueprint Layer turns hospitality into relationship, and relationship into renewal.
The post-stay layer of transformation and guest continuity.
Core Features:
Personalized regenerative protocol developed from in-stay diagnostics and narrative input
3-6-12 month continuity programs
Virtual clinician sessions and health coaching
Supplement, peptide, and hormone delivery
Seasonal recalibration and integration planning
Cross-property protocol migration and calendar syncing for return visits
Key Outcomes:
Maintains therapeutic gains beyond the stay
Encourages seasonal return visits to Hamak Hotels properties
Builds lifetime guest loyalty and increases LTV (lifetime value)
Establishes Hamak Hotels as a source of year-round, precision care-not just hospitality

HAMAK HOTELS PROPERTIES
Each HAMAK HOTELS property is its own ecosystem—with architectural tone and cultural context. ORA designs both the Wellness and Regenerative Layers to meet the distinct rhythm and narrative of each space. Below is how these layers would be adapted, attuned, and brought to life in 2 of HAMAK HOTELS properties:
Tropicana Hotel, Los Cabos
ORA LOUNGE - the the meeting space of this iconic hotel in downtown San Jose del Cabo
Wellness Layer: Deeply parasympathetic programming. Barefoot fascia walks, fascia-focused bodywork, jungle hydrotherapy, and PLASM biophysics rituals are delivered with minimal interruption. Botanical elixirs are designed to mirror local mycological and adaptogenic profiles. This is a place for the overstimulated to come back into coherence.
Regenerative Layer: Clinical interventions are offered within a small boutique space - offering one-one or small group experiences involving IVs, Stem Cells, Exosomes, NAD, Peptides, Nutraceuticals that are regenerative and rejuvenative. Small boutique dispensary on site - with peptides, hormones, supplements. Biophysics units that render this Cabo’s most boutique and personalized biohacking lounge. Accessible to Tropicana guests and members of the ORA lounge programs.
El Sanctuario Resort, Valle de Bravo
EXECUTIVE programs, and LONGEVITY programs
EXECUTIVE PROGRAMS: Business teams and executive guests that visit El Sanctuatio during the week receive specilized programs that are both wellness based and regenerative based. Bio-optimized CEOs and professional teams are the future of business success. These programs are designed to optimize the brain, the body and render professionals and their teams ready for focus and success.
LONGEVITY PROGRAMS: El Sanctuario receives guests from CDMX on the weekends. They come to relax, restore and have time in a peaceful and natural setting. We will be adding wellness and regenerative layers to their experience, so that this destination will be a place of rejuvenation and regeneration as well.

REVENUE & VALUE MULTIPLIER STRATEGY
Potential per-room uplift impact:
Wellness Layer: +$500–$2,000 per guest per day in therapies, product upsell, and virtual continuity
Regenerative Layer: +$2,000–$9,000 per guest per day in diagnostics, biologics, and long-tail protocols
Blueprint Layer: +$2,000–$10,000 per guest annually via virtual follow-up, supplement + peptide subscriptions, and return visit loyalty
Projected Monthly Uplift per Property
Assuming a 60% occupancy rate and a 30–50% guest uptake across ORA offerings:
Average Daily Revenue Uplift per Active Room: $1,200–$2,000
Estimated Monthly Revenue Increase: $216,000–$360,000 per property
This projection reflects a combination of on-site therapies, diagnostics, clinical interventions (where applicable), and virtual continuity services.
Annual Revenue Uplift per Property:
Approximately $2.5M–$4.3M+, depending on uptake rate and layering.
Long-Tail ROI Includes:
Extended guest lifecycle (via the Blueprint Layer)
Cross-property guest migration
Seasonal recalibration visits
Subscription-based follow-up care and retail purchases
Revenue Channels Activated:
ORA Boutique (In-Room + Virtual): Guests can purchase therapeutic technologies they experience onsite—PLASM biophysics units, red light panels, PEMF mats, and sleep optimization tools—ranging from $500 to $15,000+ per unit. These are shipped globally post-stay.
Supplement, Peptide, and Hormone Protocols: Guests are prescribed personalized stacks as part of the Blueprint Layer, with direct-to-consumer fulfillment through the ORA platform (100%+ margin on most products).
Onsite Therapeutic Services (Wellness Layer): Includes somatic bodywork, sound therapy, hydrotherapy, fascia treatment, and neuroacoustic journeys—all bookable experiences with 60–75% margin potential.
Clinical Services (Regenerative Layer): Diagnostics, IV infusions, peptide therapies, and biologics administered under COFEPRIS compliance in bespoke, sensorially aligned clinical suites or mobile setups.
Virtual Continuity (Blueprint Layer): Year-long virtual protocols, follow-up consultations, seasonal updates, and delivery subscriptions—generating recurring revenue while strengthening brand loyalty.
Cross-Property Regenerative Migration: The Blueprint plan invites guests to return every 3–6 months to another Hamak Hotels location, creating intra-brand guest flow and maximizing LTV (lifetime value).
Brand & Asset Value Lift
Category Leadership: HAMAK HOTELS becomes the first hospitality portfolio in LATAM to integrate full-spectrum regenerative programming—setting a global precedent beyond typical spa or wellness add-ons.
Increased ADR (Average Daily Rate): With ORA layers embedded, properties can justifiably raise room rates by $300–$800 per night, supported by experiential and therapeutic depth not found in comparable boutique hotels.
Investor Signaling: Embedding longevity and biophysics-forward hospitality demonstrates alignment with the fastest growing sectors in wellness and health—attracting new types of capital, partners, and valuation multiples.
Press + Media Appeal: A hospitality concept that fuses regenerative medicine, biophysics, and poetic sensory architecture is editorially irresistible. It’s not “another spa brand”—it’s a new category.
Global Differentiation: While others install existing brands (SHA, Sensei, Soul Spring), HAMAK HOTELS designs a future. ORA is an original signature. The value accrues to the brand, not outsourced identities.
AN INVITATION TO WORK TOGETHER
HAMAK HOTELS already holds the aesthetic, emotional, and architectural intelligence that today’s luxury travellers seek. ORA uplifts this foundation, by embedding a future-forward, biologically coherent wellness and longevity rhythm into each property. Not as an external brand insert, but as a seamless extension of HAMAK HOTELS’ essence.
In a world where healing is fragmented, medicalisation is sterile, and spa culture has plateaued, the next evolution lies in integration, where biology meets beauty, and design becomes medicine.
By partnering with ORA, HAMAK HOTELS activates revenue streams it is currently leaving untouched, strengthens brand identity through innovation, and becomes an international leader in regenerative hospitality.
Working with an emergent team like ORA allows for customization, responsiveness, and originality that legacy wellness brands can’t offer. We don’t overwrite the story, you’ve already written something beautiful. We elevate it.
Let’s build something timeless, intelligent, valuable and profitable, together.
NEXT STEPS
Ideation: Portfolio Presentation to the HAMAK HOTELS Director, Board Members and Owners
Advisory Contract: Site Visit, Strategic design + Signing of Contract
Install & Operate (Phase I): Full delivery of Wellness Layer
Install & Operate Phase II (Optional): Regenerative Layer activation via clinical partnership
Install & Operate Phase III (Optional): Blueprint Layer activation with incoming guests
Together, let’s offer guests not just beauty and belonging—but biological peace, long-term vitality, and a reason to return again and again.
